PhD in Biomedical Engineering - Understanding the interaction between extracellular matrix molecules that modulate tissue turnover
Parkville, VIC
Permanent
Full-time
2 months ago
Offer DescriptionPhD positions are currently available with in the at:The extracellular matrix provides mechanical support and structure to the tissue microenvironment and is assembled from various proteins and glycoproteins, of which collagen and proteoglycans (PGs) are prominent functional components. PGs are decorated with sulphated glycosaminoglycans (GAGs) that are heterogeneous in structure, depending on the cell and tissue type of origin, and vary in a dynamic spatiotemporal manner. The structure of GAGs can be altered by intracellular enzymes before they are secreted, and by enzymes in the extracellular space. Remodelling of the extracellular matrix is a dynamic and ongoing process for many tissues, for which there is a critical interplay between the cells and cues they receive from their surrounding environment.This project will investigate interactions that occur between the extracellular matrix molecules, collagen and the glycosaminoglycan chondroitin sulphate, to understand the mechanisms that control tissue regeneration and remodelling.This project would suit a student with a biochemistry / bioengineering background, or a student that is willing to become familiar and proficient in experimental techniques including, but not limited to cell culture, in vivo models, ELISA, Western Blot, chromatography, PCR, glycobiology, and CRISPRApplicationApplicants must satisfy the requirements to enrol in a graduate research program at the University of Melbourne - for more information on the entry requirements and how to enrol -Applicants should also satisfy the requirements and apply for a Graduate Research Scholarship - for more information on eligibility and how to apply -To be considered as being competitive for a scholarship international students need to have the equivalent of at least 85%. The University of Melbourne calculates their scholarship scores on a case by case basis and primarily using academic transcripts, publications are also taken into consideration, and may marginally increase the score.All applications for a Graduate Research Scholarship require evidence of support from the research supervisor. Highly motivated candidates who are interested in completing a PhD in Biomedical Engineering and meet the criteria for enrolment are invited to contact A/Prof Farrugia.Please email your CV, academic transcript and a brief outline of your previous research experience and your future research goals toRequirementsSkills/QualificationsThis project would suit a student with a biochemistry / bioengineering background, or a student that is willing to become familiar and proficient in experimental techniques including: cell culture, in vivo models, ELISA, Western Blot, chromatography, PCR, glycobiology, and CRISPRSpecific RequirementsApplicants must have completed 4-year undergrad or Masters (with a research component) degreeApplicants must satisfy the requirements to enrol in a graduate research program at the University of Melbourne - for more information on the entry requirements and how to enrol -Applicants should also satisfy the requirements and apply for a Graduate Research Scholarship - for more information on eligibility and how to apply -To be considered as being competitive for a scholarship international students need to have the equivalent of at least 85%. The University of Melbourne calculates their scholarship scores on a case by case basis and primarily using academic transcripts, publications are also taken into consideration, and may marginally increase the score.All applications for a Graduate Research Scholarship require evidence of support from the research supervisor. Highly motivated candidates who are interested in completing a PhD in Biomedical Engineering and meet the criteria for enrolment are invited to contact A/Prof Farrugia.Additional InformationEligibility criteriaApplicants must satisfy the requirements to enrol in a graduate research program at the University of Melbourne - for more information on the entry requirements and how to enrol -Applicants should also satisfy the requirements and apply for a Graduate Research Scholarship - for more information on eligibility and how to apply -Website for additional job detailsWork Location(s)Number of offers available 2 Company/Institute University of Melbourne Country Australia State/Province Victoria City Parkville Postal Code 3010 GeofieldWhere to apply E-mailbrooke.farrugia@unimelb.edu.auContact State/ProvinceVictoria CityParkville WebsitePostal Code3010 E-Mailbrooke.farrugia@unimelb.edu.auSTATUS: EXPIRED